大西秀明 | | 新潟医療福祉大学

リハビリテーション学部

Department of Physical Therapy 理学療法学科

教員紹介

大西秀明写真

リハビリテーション学部／理学療法学科
Faculty of Rehabilitation／Department of Physical Therapy

大西秀明 Hideaki Onishi

研究・産官学連携担当副学長／教授

プロフィール

担当科目	神経筋機能解析学、理学療法ゼミ、卒業研究
専門分野	基礎理学療法学、神経科学
キーワード	体性感覚、知覚学習、運動学習、脳機能イメージング、非侵襲的脳刺激
学位・称号／取得機関／取得年	博士（障害科学）／東北大学／2000年
資格	1989 理学療法士専門理学療法士（基礎）
過去の経歴	新潟医療福祉大学設立準備室専門委員を経て現職
所属団体・学会等	日本理学療法士協会、日本基礎理学療法学会（副理事長）、日本臨床神経生理学会（代議員）、日本生体磁気学会（評議員）、全国大学理学療法学教育学会（理事長）、日本リハビリテーション医学会、日本体力医学会、新潟医療福祉学会

外部リンク

業績等

研究領域	運動と感覚（体性感覚）に関する神経生理学的研究
研究紹介	人がスムーズな動作を遂行するために必要な大脳皮質活動について、神経生理学的手法を利用して研究しています。例えば、簡単な運動を行った際の大脳皮質の活動や、触覚刺激などを与えられた際の大脳皮質の活動をミリ秒単位で詳細に解析し、大脳のどの部位がどのようなタイミングで活動しているのかを研究しています。また、様々な外的刺激（電気刺激や磁気刺激、触覚刺激など）を与えることにより、大脳皮質の興奮性を変調させ、運動制御や運動学習に応用するための研究をしています。
著書	1. Onishi H and Kameyama S Clinical Applications of Magnetoencephalography Somatosensory system, Clinical Application obimatsu S and Kakigi R Springer 2016 73-93 2. 大西秀明リハビリテーション神経科学随意運動・他動運動・体性感覚刺激と皮質活動鈴木俊明、大西秀明メジカルビュー 2019 122-139 3. 大西秀明感覚入力で挑む感覚入力と脳の可塑性齋藤秀之，金子文成文光堂 2016 170-179 4. 大西秀明「筋電図１_運動学実習」「筋電図２_臨床運動学」「腕立て伏せ」運動学テキスト小柳麿毅，西村敦，山下脇子，大西秀明金原出版 2016 37-59, 533-544 5. 大西秀明神経の構造と機能運動療法学第2版市橋則明文光堂 2013 90-104 6. 大西秀明「論文投稿」「研究助成」理学療法研究法第3版内山靖，島田裕之医学書院 2013 254-263，266-267 7. 大西秀明，久保雅義運動機能解析テクニック理学療法ハンドブック改訂版・第1巻細田多穂・他協同医書 2010 8. 大西秀明随意運動のメカニズム運動療法学総論第2版吉尾雅春医学書院 2010 9. 大西秀明正常歩行と異常歩行運動学テキスト藤縄理南江堂 2010 10. 大西秀明「脳科学の進歩と理学療法の接点－過去から現在－」「ＭＥＧ」脳科学と理学療法大西秀明，森岡周三輪書店 2008 11. 大西秀明機能的電気刺激法物理療法沖田実・他神陵文庫 2008 12. 大西秀明筋電図のみかた図解理学療法検査・測定ガイド内山靖，他文光堂 2005 13. 大西秀明筋電計臨床動作分析マニュアル黒川幸雄，大西秀明，他文光堂 2005 14. 大西秀明神経－筋機能の計測計測法入門内山靖，他協同医書出版社 2001 15. 大西秀明ステップ昇降動作運動分析高橋正明，他三輪書店 2000
研究論文（英文）	1. Onishi H, Nagasaka K, Yokota H, Kojima S, Ohno K, Sakurai N, Kodama N, Sato D, Otsuru N. Association between somatosensory sensitivity and regional gray matter volume in healthy young volunteers: a voxel-based morphometry study Cereb Cortex 2022/5/17 10.1093/cercor/bhac188 2. Kitatani R, Furukawa K, Sakaue D, Otsuru N, Onishi H. Influences of different cognitive loads on central common neural drives to the ankle muscles during dual-task walking Neurosci Lett 2023/3/29 10.1016/j.neulet.2023.137214 3. Sasaki R, Watanabe H, Onishi H. Therapeutic benefits of noninvasive somatosensory cortex stimulation on cortical plasticity and somatosensory function: A systematic review Eur J Neurosci 2022/7/9 10.1111/ejn.15767 4. Saito K, Otsuru N, Inukai Y, Kojima S, Miyaguchi S, Nagasaka K, Onishi H. Effect of Transcranial Electrical Stimulation over the Posterior Parietal Cortex on Tactile Spatial Discrimination Performance Neuroscience 2022/5/15 10.1016/j.neuroscience.2022.05.010 5. Shiga K, Miyaguchi S, Inukai Y, Otsuru N, Onishi H. Transcranial direct current stimulation over the right intraparietal sulcus improves response inhibition Behav Brain Res 2022/9/12 10.1016/j.bbr.2022.114110 6. Kawakami S, Inukai Y, Ikarashi H, Watanabe H, Miyaguchi S, Otsuru N, Onishi H. Transcranial direct current stimulation and transcranial random noise stimulation over the cerebellum differentially affect the cerebellum and primary motor cortex pathway J Clin Neurosci 2022/4/14 10.1016/j.jocn.2022.04.003 7. Yokota H, Edama M, Hirabayashi R, Sekine C, Otsuru N, Saito K, Kojima S, Miyaguchi S, Onishi H. Effects of Stimulus Frequency, Intensity, and Sex on the Autonomic Response to Transcutaneous Vagus Nerve Stimulation Brain Sci 2022/8/26 10.3390/brainsci12081038 8. Kamii Y, Kojima S, Onishi H. Transcranial direct current stimulation over the posterior parietal cortex improves visuomotor performance and proprioception in the lower extremities Front Hum Neurosci 2022/9/5 10.3389/fnhum.2022.876083 9. Morishita S, Tsubaki A, Hotta K, Inoue T, Kojima S, Qin W, Sato D, Shirayama A, Ito Y, Onishi H. Perceived Exertion Correlates with Multiple Physiological Parameters During Cardiopulmonary Exercise Testing Adv Exp Med Biol 2022/12/17 10.1007/978-3-031-14190-4_69 10. Pham MV, Saito K, Miyaguchi S, Watanabe H, Ikarashi H, Nagasaka K, Yokota H, Kojima S, Inukai Y, Otsuru N, Onishi H. Changes in excitability and GABAergic neuronal activity of the primary somatosensory cortex after motor learning Front Neurosci 2022/10/7 10.3389/fnins.2022.794173 11. Shibata S, Watanabe T, Matsumoto T, Yunoki K, Horinouchi T, Kirimoto H, Zhang J, Wang H, Wu J, Onishi H, Mima T. Triple tSMS system ("SHIN jiba") for non-invasive deep brain stimulation: a validation study in healthy subjects J Neuroeng Rehabil 2022/11/24 10.1186/s12984-022-01110-7 12. Shibata S, Watanabe T, Otsuru N, Onishi H, Mima T. Very low-frequency transcranial electrical stimulation over the primary motor area can influence the voluntary movement initiation in humans Brain Stimul 2023/2/3 10.1016/j.brs.2023.01.1679 13. Sakurai N, Nagasaka K, Takahashi S, Kasai S, Onishi H, Kodama N. Brain function effects of autonomous sensory meridian response (ASMR) video viewing Front Neurosci 2023/2/13 10.3389/fnins.2023.1025745 14. Miyaguchi S, Inukai Y, Mitsumoto S, Otsuru N, Onishi H. Gamma-transcranial alternating current stimulation on the cerebellum and supplementary motor area improves bimanual motor skill. Behav Brain Res. 2022/2/19 16:113805. doi:10.1016/j.bbr.2022.113805 15. Nagasaka K, Otsuru N, Sato R, Watanabe H, Sakurai N, Ohno K, Kodama N, Onishi H. Cortical signature related to psychometric properties of pain vigilance in healthy individuals: A voxel-based morphometric study. Neurosci Lett. 2022/1/10 16: 772:136445. doi:10.1016/j.neulet.2022.136445 16. Ikarashi H, Otsuru N, Yokota H, Nagasaka K, Igarashi K, Miyaguchi S, Onishi H. Influence of Catechol-O-Methyltransferase Gene Polymorphism on the Correlation between Alexithymia and Hypervigilance to Pain. Int J Environ Res Public Health. 2021/12/24 16: 18(24):13265. doi:10.3390/ijerph182413265 17. Sasaki R, Miyaguchi S, Onishi H. Effect of brain-derived neurotrophic factor gene polymorphisms on motor performance and motor learning: A systematic review and meta-analysis. Behav Brain Res. 2021/12/16 26: 420:113712. doi:10.1016/j.bbr.2021.113712 18. Kojima S, Miyaguchi S, Yokota H, Saito K, Inukai Y, Otsuru N, Onishi H. The Number or Type of Stimuli Used for Somatosensory Stimulation Affected the Modulation of Corticospinal Excitability. Brain Sci. 2021/11/27 12: 11(11):1494. doi:10.3390/brainsci11111494 19. Sasaki R, Kojima S, Onishi H. Do Brain-Derived Neurotrophic Factor Genetic Polymorphisms Modulate the Efficacy of Motor Cortex Plasticity Induced by Non-invasive Brain Stimulation? A Systematic Review. Front Hum Neurosci. 2021/10/15 28: 15:742373. doi:10.3389/fnhum.2021.742373 20. Watanabe H, Kojima S, Nagasaka K, Ohno K, Sakurai N, Kodama N, Otsuru N, Onishi H. Gray Matter Volume Variability in Young Healthy Adults: Influence of Gender Difference and Brain-Derived Neurotrophic Factor Genotype. Cereb Cortex. 2021/10/12 11:bhab370. doi:10.1093/cercor/bhab370 21. Miyaguchi S, Inukai Y, Hashimoto I, Otsuru N, Onishi H. Sleep affects the motor memory of basketball shooting skills in young amateurs. J Clin Neurosci. 2021/11/30 96:187-193. doi:10.1016/j.jocn.2021.11.016 22. Sakai S, Saito K, Kojima S, Otsuru N, Onishi H. Grating orientation task trial numbers for short- and long-term tactile discrimination learning. J Clin Neurosci. 2021/10/17 93:195-199. doi:10.1016/j.jocn.2021.08.026 23. Sakurai N, Ohno K, Kasai S, Nagasaka K, Onishi H, Kodama N. Induction of Relaxation by Autonomous Sensory Meridian Response. Front Behav Neurosci. 2021/12/17 30: 15:761621. doi:10.3389/fnbeh.2021.761621 24. Otsuru N, Ogawa M, Yokota H, Miyaguchi S, Kojima S, Saito K, Inukai Y, Onishi H. Auditory change-related cortical response is associated with hypervigilance to pain in healthy volunteers. Eur J Pain. 2021/9/16 19: 100(46):e27822. doi:10.1097/MD 25. Hirabayashi R, Edama M, Saito A, Yamada Y, Nawa R, Onishi H. Effects of Clenching Strength on Exercise Performance: Verification Using Spinal Function Assessments Sports Health 2021/5/31 10.1177/19417381211014836 26. Hoshi H, Kojima S, Otsuru N, Onishi H. Effects of transcranial random noise stimulation timing on corticospinal excitability and motor function. Behav Brain Res. 2021/7/24 24: 414:113479. doi:10.1016/j.bbr.2021.113479 27. Sasaki R, Watanabe H, Miyaguchi S, Otsuru N, Ohno K, Sakurai N, Kodama N, Onishi H. Contribution of the brain-derived neurotrophic factor and neurometabolites to the motor performance Behav Brain Res 2021/6/27 10.1016/j.bbr.2021.113433 28. Sasaki R, Otsuru N, Miyaguchi S, Kojima S, Watanabe H, Ohno K, Sakurai N, Kodama N, Sato D, Onishi H. Influence of Brain-Derived Neurotrophic Factor Genotype on Short-Latency Afferent Inhibition and Motor Cortex Metabolites Brain Sci 2021/4/3 10.3390/brainsci11030395 29. Tsubaki A, Morishita S, Hotta K, Tokunaga Y, Qin W, Kojima S, Onishi H. Changes in the Laterality of Oxygenation in the Prefrontal Cortex and Premotor Area During a 20-Min Moderate-Intensity Cycling Exercise Adv Exp Med Biol 2021/5/9 10.1007/978-3-030-48238-1_18 30. Morishita S, Tsubaki A, Hotta K, Kojima S, Sato D, Shirayama A, Ito Y, Onishi H. Relationship Between the Borg Scale Rating of Perceived Exertion and Leg-Muscle Deoxygenation During Incremental Exercise in Healthy Adults Adv Exp Med Biol 2021/5/9 10.1007/978-3-030-48238-1_15 31. 他，多数
研究論文（和文）	1. 中尾真理, 大西秀明, 浅川育世, 田上未来, 出江紳一支援機器開発における多分野多職種連携の課題と専門医がリハビリテーション科医師に求める能力　リハビリテーション科専門医に施行したアンケート結果から The Japanese Journal of Rehabilitation Medicine 2022.10.24. 59巻12号 Page1248-1258
科学研究費	1. 2020-2023年度挑戦的研究（開拓）小脳の構造・機能・ネットワーク解析による「研ぎ澄まされた感覚」の可視化 2. 2019-2023年度基盤研究（A）知覚学習イノベーション－次世代感覚運動学習法の創出を目指してー 3. 2016-2018年度基盤研究（B）運動学習および感覚学習過程における皮質内抑制回路の役割 4. 2013-2015年度基盤研究（B）運動遂行に伴う感覚情報処理に関する神経基盤の解明－ＭＥＧとＴＭＳを併用した研究－ 5. 2010-2012年度基盤研究（B）運動遂行に伴う感覚情報処理機構の解明－脳磁図を用いた研究－ 6. 2009-2011年度挑戦的研究（萌芽）運動遂行時における脳血液量と体循環との関係 7. 2007-2009年度基盤研究（B）運動遂行時における一次感覚野および運動前野の役割について-脳磁図を用いた研究- 8. 2005-2006年度若手研究ヒト随意運動時における筋出力および関節角度変化が運動関連脳磁場に与える影響 9. 2003-2004年度若手研究膝関節6自由度運動解析と臨床応用
共同研究・受託研究等	1. 2023- 厚生労働省支援機器の開発・普及のためのモデル拠点構築に資する研究 2. 2020-2022年度厚生労働省障害者の支援機器開発に携わる医療・福祉・工学分野の人材育成モデル構築に資する研究
学会等研究発表	1. 大槻智史，長坂和明，大鶴直史，大西秀明 Neural response in the posterior insular cortex evoked by stimulation of the basolateral amygdala in central post-stroke pain model rats 第100回日本生理学会 2023/3/14 2. 芝田純也、大鶴直史、大西秀明、美馬達哉運動関連脳電位と随意運動との因果関係－運動関連脳電位を模した経頭蓋電気刺激は随意運動を誘発できるか？－第52回日本臨床神経生理学会学術大会 2022/11/24-11/26 3. 鈴木孝昇, 長坂和明, 大槻智史, 大鶴直史, 大西秀明青斑核への持続的な1.0Hz電気刺激は一次体性感覚野の活動を増大させる一麻酔下動物実験による検証一第22回新潟医療福祉学会学術集会 2022/10/29 4. 齊藤慧，大鶴直史，小池康太郎，竹内皓太，大西秀明背外側前頭前野への経頭蓋ランダムノイズ刺激が触覚方位弁別能力にもたらす効果第27回日本基礎理学療法学会学術大会 2022/10/1-2 5. 鈴木孝昇, 長坂和明, 大槻智史, 大鶴直史, 大西秀明ラット青斑核への電気刺激が一次体性感覚野の神経活動へ与える影響第27回日本基礎理学療法学会学術大会 2022/10/1-2 6. 平林怜，江玉睦明，岡田芳幸，山田勇輝，阿部明日香，大河内偉琉，中島早紀，横田裕丈，関根千恵，大西秀明咬合圧バランスによる遠隔促通効果が青斑核と脊髄興奮性に及ぼす影響第27回日本基礎理学療法学会学術大会 2022/10/1-2 7. 川上紗輝，犬飼康人，五十嵐眸実，神居寧，宮口翔太，大鶴直史，大西秀明小脳への経頭蓋ランダムノイズ刺激が運動学習および脳活動に及ぼす影響第27回日本基礎理学療法学会学術大会 2022/10/1-2 8. 神居寧，小島翔，大西秀明課題難易度の異なる運動練習が下肢の皮質脊髄路興奮性および抑制性に及ぼす影響第27回日本基礎理学療法学会学術大会 2022/10/1-2 9. 三木陽菜乃，齊藤慧，平賀大河，宮口翔太，大鶴直史，大西秀明脳由来神経栄養因子が抹消電気刺激の刺激効果にもたらす影響～触覚方位弁別課題を用いた検証～第27回日本基礎理学療法学会学術大会 2022/10/1-2 10. 五十嵐眸実，大鶴直史，長坂和明，宮口翔太，Jose Gomez-Tames，平田晃正，大西秀明背外側前頭前野に対する経頭蓋交流電流刺激による鎮痛効果-電界シミュレーションによる検討- 第27回日本基礎理学療法学会学術大会 2022/10/1-2 11. 横田裕丈，江玉睦明，平林怜，関根千恵，阿久澤弘，石垣智恒，大鶴直史，齊藤　慧，小島　翔，宮口翔太，大西秀明異なる電流強度による経皮的迷走神経刺激が自律神経活動に及ぼす影響第27回日本基礎理学療法学会学術大会 2022/10/1-2 12. 髙橋ひろな，犬飼康人，宮口翔太，大鶴直史，大西秀明前庭ノイズ電流刺激がファンクショナルリーチテストに与える影響第28回脳機能とリハビリテーション研究会学術集会 2022/9/1-9/23 13. 田邊かこ，小島翔，大西秀明視覚情報の提示条件の違いがActive Touch介入効果に及ぼす影響第28回脳機能とリハビリテーション研究会学術集会 2022/9/1-9/23 14. 大槻智史，長坂和明，大鶴直史，大西秀明扁桃体外側基底核の電気刺激によって誘発される後部島皮質の神経活動応答‐脳卒中後疼痛モデルラットを対象とした計測第28回脳機能とリハビリテーション研究会学術集会 2022/9/1-9/23 15. 川上紗輝，犬飼康人，五十嵐眸実，神居寧，宮口翔太，大鶴直史，大西秀明小脳への経頭蓋ランダムノイズ刺激による脳活動と運動学習の関連性第28回脳機能とリハビリテーション研究会学術集会 2022/9/1-9/23 16. 神居寧，小島翔，大西秀明後頭頂皮質に対する経頭蓋電流刺激が下肢の視覚追従課題および固有受容覚に及ぼす影響第28回脳機能とリハビリテーション研究会学術集会 2022/9/1-9/23 17. 志賀恭介，宮口翔太，犬飼康人，大鶴直史，大西秀明右頭頂間溝への経頭蓋直流電流刺激が反応抑制機能に与える影響第28回脳機能とリハビリテーション研究会学術集会 2022/9/1-9/23 18. 五十嵐眸実，大鶴直史，長坂和明，宮口翔太，Jose Gomez-Tames，平田晃正，大西秀明電界シミュレーションを用いた経頭蓋交流電流による鎮痛効果の検討第28回脳機能とリハビリテーション研究会学術集会 2022/9/1-9/23 19. 丸山雄基，小島翔，大西秀明刺激様式の異なる触圧覚刺激介入が触圧覚刺激の移動方向識別能力に及ぼす影響第28回脳機能とリハビリテーション研究会学術集会 2022/9/1-9/23 20. 鈴木孝昇, 長坂和明, 大槻智史, 大鶴直史, 大西秀明 1.0 Hzのラット青斑核電気刺激は一次体性感覚野の活動を増大させる第28回脳機能とリハビリテーション研究会学術集会 2022/9/1-9/23 21. 芝田純也、大西秀明、美馬達哉シン磁場刺激（triple tSMS）がもたらす皮質内興奮性調節機構への影響第16回Motor Control 研究会 2022/8/25-27 22. Suzuki T, Nagasaka K, Otsuki T, Otsuru N, Onishi H. The effects of tonic locus coeruleus output on forepaw-evoked response of the primary somatosensory cortex in anesthetized rats 第45回日本神経科学大会 2022/6/30-7/3 23. Shibata S, Mima T, Onishi H A brand-new transcranial static magnetic field stimulation (triple tSMS) of human motor cortex 第45回日本神経科学大会 2022/6/30-7/3 24. その他，多数
学会・職能団体の委員	1. 2023 全国大学理学療法学教育学会理事長 2. 2023 日本基礎理学療法学会副理事長 3. 2023 日本生体磁気学会評議員 4. 2023 日本臨床神経生理学会代議員 5.
学内委員会活動	1. 将来計画機構運営委員会（委員長） 2. 研究産官学連携推進機構・運営委員会（委員長） 3. 自己点検・評価委員会 4. 学部評価準備委員会 5. 知的財産委員会 6. 利益相反マネジメント委員会 7. 運動機能医科学研究所（運営委員）

Profile

Research Areas	Neuroscience
Research Introduction	sensorimotor integration / motor and perceptual learning
Books	Onishi H: Somatosensory system. Tobimatsu S and Kakigi R ed. Clinical Applications of Magnetoencephalography. Springer. 2016
Papers	1. 2022 Onishi H, Nagasaka K, Yokota H, Kojima S, Ohno K, Sakurai N, Kodama N, Sato D, Otsuru N. Association between somatosensory sensitivity and regional gray matter volume in healthy young volunteers: a voxel-based morphometry study Cereb Cortex 2022/5/17 10.1093/cercor/bhac188 2. 2022 Kitatani R, Furukawa K, Sakaue D, Otsuru N, Onishi H. Influences of different cognitive loads on central common neural drives to the ankle muscles during dual-task walking Neurosci Lett 2023/3/29 10.1016/j.neulet.2023.137214 3. 2022 Sasaki R, Watanabe H, Onishi H. Therapeutic benefits of noninvasive somatosensory cortex stimulation on cortical plasticity and somatosensory function: A systematic review Eur J Neurosci 2022/7/9 10.1111/ejn.15767 4. 2022 Saito K, Otsuru N, Inukai Y, Kojima S, Miyaguchi S, Nagasaka K, Onishi H. Effect of Transcranial Electrical Stimulation over the Posterior Parietal Cortex on Tactile Spatial Discrimination Performance Neuroscience 2022/5/15 10.1016/j.neuroscience.2022.05.010 5. 2022 Shiga K, Miyaguchi S, Inukai Y, Otsuru N, Onishi H. Transcranial direct current stimulation over the right intraparietal sulcus improves response inhibition Behav Brain Res 2022/9/12 10.1016/j.bbr.2022.114110 6. 2022 Kawakami S, Inukai Y, Ikarashi H, Watanabe H, Miyaguchi S, Otsuru N, Onishi H. Transcranial direct current stimulation and transcranial random noise stimulation over the cerebellum differentially affect the cerebellum and primary motor cortex pathway J Clin Neurosci 2022/4/14 10.1016/j.jocn.2022.04.003 7. 2022 Yokota H, Edama M, Hirabayashi R, Sekine C, Otsuru N, Saito K, Kojima S, Miyaguchi S, Onishi H. Effects of Stimulus Frequency, Intensity, and Sex on the Autonomic Response to Transcutaneous Vagus Nerve Stimulation Brain Sci 2022/8/26 10.3390/brainsci12081038 8. 2022 Kamii Y, Kojima S, Onishi H. Transcranial direct current stimulation over the posterior parietal cortex improves visuomotor performance and proprioception in the lower extremities Front Hum Neurosci 2022/9/5 10.3389/fnhum.2022.876083 9. 2022 Morishita S, Tsubaki A, Hotta K, Inoue T, Kojima S, Qin W, Sato D, Shirayama A, Ito Y, Onishi H. Perceived Exertion Correlates with Multiple Physiological Parameters During Cardiopulmonary Exercise Testing Adv Exp Med Biol 2022/12/17 10.1007/978-3-031-14190-4_69 10. 2022 Pham MV, Saito K, Miyaguchi S, Watanabe H, Ikarashi H, Nagasaka K, Yokota H, Kojima S, Inukai Y, Otsuru N, Onishi H. Changes in excitability and GABAergic neuronal activity of the primary somatosensory cortex after motor learning Front Neurosci 2022/10/7 10.3389/fnins.2022.794173 11. 2022 Shibata S, Watanabe T, Matsumoto T, Yunoki K, Horinouchi T, Kirimoto H, Zhang J, Wang H, Wu J, Onishi H, Mima T. Triple tSMS system ("SHIN jiba") for non-invasive deep brain stimulation: a validation study in healthy subjects J Neuroeng Rehabil 2022/11/24 10.1186/s12984-022-01110-7 12. 2022 Shibata S, Watanabe T, Otsuru N, Onishi H, Mima T. Very low-frequency transcranial electrical stimulation over the primary motor area can influence the voluntary movement initiation in humans Brain Stimul 2023/2/3 10.1016/j.brs.2023.01.1679 13. 2022 Sakurai N, Nagasaka K, Takahashi S, Kasai S, Onishi H, Kodama N. Brain function effects of autonomous sensory meridian response (ASMR) video viewing Front Neurosci 2023/2/13 10.3389/fnins.2023.1025745 14. 2021 Miyaguchi S, Inukai Y, Mitsumoto S, Otsuru N, Onishi H. Gamma-transcranial alternating current stimulation on the cerebellum and supplementary motor area improves bimanual motor skill. Behav Brain Res. 2022/2/19 16:113805. doi:10.1016/j.bbr.2022.113805 15. 2021 Nagasaka K, Otsuru N, Sato R, Watanabe H, Sakurai N, Ohno K, Kodama N, Onishi H. Cortical signature related to psychometric properties of pain vigilance in healthy individuals: A voxel-based morphometric study. Neurosci Lett. 2022/1/10 16: 772:136445. doi:10.1016/j.neulet.2022.136445 16. 2021 Ikarashi H, Otsuru N, Yokota H, Nagasaka K, Igarashi K, Miyaguchi S, Onishi H. Influence of Catechol-O-Methyltransferase Gene Polymorphism on the Correlation between Alexithymia and Hypervigilance to Pain. Int J Environ Res Public Health. 2021/12/24 16: 18(24):13265. doi:10.3390/ijerph182413265 17. 2021 Sasaki R, Miyaguchi S, Onishi H. Effect of brain-derived neurotrophic factor gene polymorphisms on motor performance and motor learning: A systematic review and meta-analysis. Behav Brain Res. 2021/12/16 26: 420:113712. doi:10.1016/j.bbr.2021.113712 18. 2021 Kojima S, Miyaguchi S, Yokota H, Saito K, Inukai Y, Otsuru N, Onishi H. The Number or Type of Stimuli Used for Somatosensory Stimulation Affected the Modulation of Corticospinal Excitability. Brain Sci. 2021/11/27 12: 11(11):1494. doi:10.3390/brainsci11111494 19. 2021 Sasaki R, Kojima S, Onishi H. Do Brain-Derived Neurotrophic Factor Genetic Polymorphisms Modulate the Efficacy of Motor Cortex Plasticity Induced by Non-invasive Brain Stimulation? A Systematic Review. Front Hum Neurosci. 2021/10/15 28: 15:742373. doi:10.3389/fnhum.2021.742373 20. 2021 Watanabe H, Kojima S, Nagasaka K, Ohno K, Sakurai N, Kodama N, Otsuru N, Onishi H. Gray Matter Volume Variability in Young Healthy Adults: Influence of Gender Difference and Brain-Derived Neurotrophic Factor Genotype. Cereb Cortex. 2021/10/12 11:bhab370. doi:10.1093/cercor/bhab370 21. 2021 Miyaguchi S, Inukai Y, Hashimoto I, Otsuru N, Onishi H. Sleep affects the motor memory of basketball shooting skills in young amateurs. J Clin Neurosci. 2021/11/30 96:187-193. doi:10.1016/j.jocn.2021.11.016 22. 2021 Sakai S, Saito K, Kojima S, Otsuru N, Onishi H. Grating orientation task trial numbers for short- and long-term tactile discrimination learning. J Clin Neurosci. 2021/10/17 93:195-199. doi:10.1016/j.jocn.2021.08.026 23. 2021 Sakurai N, Ohno K, Kasai S, Nagasaka K, Onishi H, Kodama N. Induction of Relaxation by Autonomous Sensory Meridian Response. Front Behav Neurosci. 2021/12/17 30: 15:761621. doi:10.3389/fnbeh.2021.761621 24. 2021 Otsuru N, Ogawa M, Yokota H, Miyaguchi S, Kojima S, Saito K, Inukai Y, Onishi H. Auditory change-related cortical response is associated with hypervigilance to pain in healthy volunteers. Eur J Pain. 2021/9/16 19: 100(46):e27822. doi:10.1097/MD 25. 2021 Hirabayashi R, Edama M, Saito A, Yamada Y, Nawa R, Onishi H. Effects of Clenching Strength on Exercise Performance: Verification Using Spinal Function Assessments Sports Health 2021/5/31 10.1177/19417381211014836 26. 2021 Hoshi H, Kojima S, Otsuru N, Onishi H. Effects of transcranial random noise stimulation timing on corticospinal excitability and motor function. Behav Brain Res. 2021/7/24 24: 414:113479. doi:10.1016/j.bbr.2021.113479 27. 2021 Sasaki R, Watanabe H, Miyaguchi S, Otsuru N, Ohno K, Sakurai N, Kodama N, Onishi H. Contribution of the brain-derived neurotrophic factor and neurometabolites to the motor performance Behav Brain Res 2021/6/27 10.1016/j.bbr.2021.113433 28. 2021 Sasaki R, Otsuru N, Miyaguchi S, Kojima S, Watanabe H, Ohno K, Sakurai N, Kodama N, Sato D, Onishi H. Influence of Brain-Derived Neurotrophic Factor Genotype on Short-Latency Afferent Inhibition and Motor Cortex Metabolites Brain Sci 2021/4/3 10.3390/brainsci11030395 29. 2021 Tsubaki A, Morishita S, Hotta K, Tokunaga Y, Qin W, Kojima S, Onishi H. Changes in the Laterality of Oxygenation in the Prefrontal Cortex and Premotor Area During a 20-Min Moderate-Intensity Cycling Exercise Adv Exp Med Biol 2021/5/9 10.1007/978-3-030-48238-1_18 30. 2021 Morishita S, Tsubaki A, Hotta K, Kojima S, Sato D, Shirayama A, Ito Y, Onishi H. Relationship Between the Borg Scale Rating of Perceived Exertion and Leg-Muscle Deoxygenation During Incremental Exercise in Healthy Adults Adv Exp Med Biol 2021/5/9 10.1007/978-3-030-48238-1_15 31. 他，多数 Researchmap: https://researchmap.jp/read0191448 (Recent Articles) 1. Miyaguchi S, Inukai Y, Mitsumoto S, Otsuru N, Onishi H.: Gamma-transcranial alternating current stimulation on the cerebellum and supplementary motor area improves bimanual motor skill. Behav Brain Res.2022, 16:113805. doi:10.1016/j.bbr.2022.113805 2. Nagasaka K, Otsuru N, Sato R, Watanabe H, Sakurai N, Ohno K, Kodama N, Onishi H.: Cortical signature related to psychometric properties of pain vigilance in healthy individuals: A voxel-based morphometric study. Neurosci Lett. 2022, 16: 772:136445. doi:10.1016/j.neulet.2022.136445 3. Ikarashi H, Otsuru N, Yokota H, Nagasaka K, Igarashi K, Miyaguchi S, Onishi H.: Influence of Catechol-O-Methyltransferase Gene Polymorphism on the Correlation between Alexithymia and Hypervigilance to Pain. Int J Environ Res Public Health. 2021. 16: 18(24):13265. doi:10.3390/ijerph182413265 4. Sakurai N, Ohno K, Kasai S, Nagasaka K, Onishi H, Kodama N.: Induction of Relaxation by Autonomous Sensory Meridian Response. Front Behav Neurosci. 2021, 30: 15:761621. doi:10.3389/fnbeh.2021.761621 5. Sasaki R, Miyaguchi S, Onishi H.: Effect of brain-derived neurotrophic factor gene polymorphisms on motor performance and motor learning: A systematic review and meta-analysis. Behav Brain Res. 2022, 26: 420:113712. doi:10.1016/j.bbr.2021.113712 6. Miyaguchi S, Inukai Y, Hashimoto I, Otsuru N, Onishi H.: Sleep affects the motor memory of basketball shooting skills in young amateurs. J Clin Neurosci. 2022, 96:187-193. doi:10.1016/j.jocn.2021.11.016 7. Kojima S, Miyaguchi S, Yokota H, Saito K, Inukai Y, Otsuru N, Onishi H.: The Number or Type of Stimuli Used for Somatosensory Stimulation Affected the Modulation of Corticospinal Excitability. Brain Sci. 2021, 12: 11(11):1494. doi:10.3390/brainsci11111494 8. Morishita S, Hirabayashi R, Tsubaki A, Aoki O, Fu JB, Onishi H, Tsuji T.: Relationship between balance function and QOL in cancer survivors and healthy subjects. Medicine (Baltimore)2021, 19: 100(46):e27822. doi:10.1097/MD.0000000000027822 9. Sakai S, Saito K, Kojima S, Otsuru N, Onishi H.: Grating orientation task trial numbers for short- and long-term tactile discrimination learning. J Clin Neurosci. 2021, 93:195-199. doi:10.1016/j.jocn.2021.08.026 10. Sasaki R, Kojima S, Onishi H.: Do Brain-Derived Neurotrophic Factor Genetic Polymorphisms Modulate the Efficacy of Motor Cortex Plasticity Induced by Non-invasive Brain Stimulation? A Systematic Review. Front Hum Neurosci. 2021, 28: 15:742373. doi:10.3389/fnhum.2021.742373 11. Watanabe H, Kojima S, Nagasaka K, Ohno K, Sakurai N, Kodama N, Otsuru N, Onishi H.: Gray Matter Volume Variability in Young Healthy Adults: Influence of Gender Difference and Brain-Derived Neurotrophic Factor Genotype. Cereb Cortex. 2021, 11:bhab370. doi:10.1093/cercor/bhab370 12. Otsuru N, Ogawa M, Yokota H, Miyaguchi S, Kojima S, Saito K, Inukai Y, Onishi H.: Auditory change-related cortical response is associated with hypervigilance to pain in healthy volunteers. Eur J Pain. 2022, 26(2):349-355. doi:10.1002/ejp.1863 13. Hoshi H, Kojima S, Otsuru N, Onishi H.: Effects of transcranial random noise stimulation timing on corticospinal excitability and motor function. Behav Brain Res. 2021, 24: 414:113479. doi:10.1016/j.bbr.2021.113479 14. Sasaki R, Watanabe H, Miyaguchi S, Otsuru N, Ohno K, Sakurai N, Kodama N, Onishi H.: Contribution of the brain-derived neurotrophic factor and neurometabolites to the motor performance. Behav Brain Res. 2021, 27: 412:113433. doi:10.1016/j.bbr.2021.113433 15. Oyanagi K, Kitai T, Yoshimura Y, Yokoi Y, Ohara N, Kohara N, Sakai N, Honda A, Onishi H, Iwata K.: Effect of early intensive rehabilitation on the clinical outcomes of patients with acute stroke. Geriatr Gerontol Int. 2021, 21(8):623-628. doi:10.1111/ggi.14202 16. Hirabayashi R, Edama M, Saito A, Yamada Y, Nawa R, Onishi H.: Effects of Clenching Strength on Exercise Performance: Verification Using Spinal Function Assessments. Sports Health. 2021, 29:19417381211014836. doi:10.1177/19417381211014836 17. Tsubaki A, Morishita S, Hotta K, Tokunaga Y, Qin W, Kojima S, Onishi H.: Changes in the Laterality of Oxygenation in the Prefrontal Cortex and Premotor Area During a 20-Min Moderate-Intensity Cycling Exercise. Adv Exp Med Biol. 2021, 269:113-117. doi:10.1007/978-3-030-48238-1_18 18. Morishita S, Tsubaki A, Hotta K, Kojima S, Sato D, Shirayama A, Ito Y, Onishi H.: Relationship Between the Borg Scale Rating of Perceived Exertion and Leg-Muscle Deoxygenation During Incremental Exercise in Healthy Adults. Adv Exp Med Biol. 2021, 1269:95-99. doi:10.1007/978-3-030-48238-1_15 19. Sasaki R, Otsuru N, Miyaguchi S, Kojima S, Watanabe H, Ohno K, Sakurai N, Kodama N, Sato D, Onishi H.: Influence of Brain-Derived Neurotrophic Factor Genotype on Short-Latency Afferent Inhibition and Motor Cortex Metabolites. Brain Sci. 2021, 20: 11(3):395. doi:10.3390/brainsci11030395 20. Kojima S, Otsuru N, Miyaguchi S, Yokota H, Nagasaka K, Saito K, Inukai Y, Shirozu H, Onishi H.: The intervention of mechanical tactile stimulation modulates somatosensory evoked magnetic fields and cortical oscillations. Eur J Neurosci. 2021, 53(10):3433-3446. doi:10.1111/ejn.15209 21. Yokota H, Otsuru N, Saito K, Kojima S, Miyaguchi S, Inukai Y, Nagasaka K, Onishi H.: Region-Specific Effects of 10-Hz Transcranial Alternate Current Stimulation Over the Left Posterior Parietal Cortex and Primary Somatosensory Area on Tactile Two-Point Discrimination Threshold. Front Neurosci. 2021, 18: 15:576526. doi:10.3389/fnins.2021.576526 22. Pham MV, Miyaguchi S, Watanabe H, Saito K, Otsuru N, Onishi H.: Effect of Repetitive Passive Movement Before Motor Skill Training on Corticospinal Excitability and Motor Learning Depend on BDNF Polymorphisms. Front Hum Neurosci. 2021, 5: 15:621358. doi:10.3389/fnhum.2021.621358 23. Hoshi H, Kojima S, Otsuru N, Onishi H.: Corticospinal excitability of untrained side depends on the type of motor task and degree of improvement in motor function. Brain Cogn. 2021, 148:105691. doi:10.1016/j.bandc.2021.105691 24. Yamashiro K, Yamazaki Y, Siiya K, Ikarashi K, Baba Y, Otsuru N, Onishi H, Sato D.: Modality-specific improvements in sensory processing among baseball players. Sci Rep. 2021, 26: 11(1):2248. doi:10.1038/s41598-021-81852-x 25. Saito K, Otsuru N, Yokota H, Inukai Y, Miyaguchi S, Kojima S, Onishi H.: α-tACS over the somatosensory cortex enhances tactile spatial discrimination in healthy subjects with low alpha activity. Brain Behav. 2021,11(3):e02019. doi:10.1002/brb3.2019 26. Inukai Y, Miyaguchi S, Kobayashi N, Otsuru N, Onishi H.: Noisy galvanic vestibular stimulation effect on center of pressure sway during one-legged standing. J Clin Neurosci. 2020, 82(Pt: A):173-178. doi:10.1016/j.jocn.2020.10.050 27. Morishita S, Tsubaki A, Hotta K, Inoue T, Qin W, Kojima S, Fu JB, Onishi H.: Face Pain Scale and Borg Scale compared to physiological parameters during cardiopulmonary exercise testing. J Sports Med Phys Fitness. 2021, 61(11):1464-1468. doi:10.23736/S0022-4707.20.11815-2 et al,