研究メンバー詳細情報

大鶴 直史准教授

リハビリテーション学部/理学療法学科

大鶴 直史Otsuru Naofumi

准教授

プロフィール

担当科目理学療法基礎評価学Ⅱ、物理療法学、神経筋機能解析学
専門分野神経科学、脳機能計測
学位・称号/取得機関/取得年博士(理学)/総合研究大学院大学/2010年
資格理学療法士
最終出身校総合研究大学院大学生命科学研究科生理科学専攻博士課程
過去の経歴自然科学研究機構生理学研究所博士研究員、広島大学大学院医歯薬保健学研究院助教を経て現職
所属団体・学会等日本理学療法士協会、日本臨床神経生理学会、日本生体磁気学会、日本再生医療学会、北米神経科学学会

業績等

研究領域神経科学、痛みの脳内情報処理、ニューロリハビリテーション
研究紹介リハビリテーションを必要とされる患者さんの多くが、からだに痛みを抱えておられます。その中には、治療が難しい痛みも含まれています。痛みに関連する脳活動を調べることによって、痛みがどのように生み出されるか、またどのようにすれば痛みを抑えられるかに関する研究をしています。
受賞歴4th Asian and Oceanian Congress of Clinical Neurophysiology, 2009: Travel Award
29th International Congress of Clinical Neurophysiology, 2010: Young Investigator Award
第26回日本生体磁気学会 2011年:奨励賞(35歳以下)
研究論文1. Inukai Y, Otsuru N, Masaki M, Saito K, Miyaguchi S, Kojima S, Onishi H. Effect of noisy galvanic vestibular stimulation on center of pressure sway of static standing posture. Brain Stimulation (in press).
2. Sasaki R, Nakagawa M, Tsuiki S, Miyaguchi S, Kojima S, Saito K, Inukai Y, Masaki M, Otsuru N, Onishi H: Regulation of primary motor cortex excitability by repetitive passive finger movement frequency. Neuroscience 357: 232-240, 2017
3. Yoshino A, Okamoto Y, Doi M, Otsuru N, Okada G, Takamura M, Ichikawa N, Yokoyama S, Yamashita H, Yamawaki S: Regional brain functions in the resting state indicative of potential differences between depression and chronic pain. Sci Rep 7: 3003, 2017
4. Imura T, Tomiyasu M, Otsuru N, Nakagawa K, Otsuka T, Takahasi S, Takeda M, Shrestha L, Kawahara Y, Fukazawa T, Sueda T, Tanimoto K, Yuge L: Hypoxic preconditioning increases the neuroprotective effects of mesenchymal stem cells in a rat model of spinal cord injury. J Stem Cell Res Ther 7: 375, 2017
5. Inukai Y, Saito K, Sasaki R, Tsuiki S, Miyaguchi S, Kojima S, Masaki M, Otsuru N, Onishi H: Comparison of three non-invasive transcranial electrical stimulation methods for increasing cortical excitability. Front Hum Neurosci 10: 668, 2016
6. Yoshino A, Okamoto Y, Doi M, Horikoshi M, Oshita K, Nakamura R, Otsuru N, Yoshimura S, Tanaka K, Takagaki K, Jinnin R, Yamashita H, Kawamoto M, Yamawaki S: Effectiveness of group cognitive behavioral therapy (GCBT) for somatoform pain disorder patients in Japan: A preliminary non-case-control study. Psychiat Clin Neurosci 69: 763-772, 2015
7. Nishihara M, Inui K, Morita T, Kodaira M, Mochizuki H, Otsuru N, Motomura E, Ushida T, Kakigi R: Echoic memory: Investigation of its temporal resolution analyzed by auditory offset cortical responses. PLOS ONE 9: e106553, 2014
8. Otsuru N, Hashizume A, Nakamura D, Endo Y, Inui K, Kakigi R, Yuge L: Sensory incongruence leading to hand disownership modulates somatosensory cortical processing. Cortex 58:1-8, 2014
9. Nakagawa K, Otsuru N, Inui K, Kakigi R: Change-related auditory P50: A MEG study. NeuroImage 86:131 -137, 2014
10. Omori S, Isose S, Otsuru N, Nishihara M, Kuwabara S, Inui K, Kakigi R: Somatotopic representation of pain in the primary somatosensory cortex (SI) in humans. Clin Neurophysiol 124:1422-1430, 2013
11. Otsuru N, Tsuruhara A, Motomura E, Tanii H, Nishihara M, Inui K, Kakigi R: Effects of acute nicotine on auditory change-related cortical responses. Psychopharmacology 224:327-335, 2012
12. Ohoyama K, Motomura E, Inui K, Nishihara M, Otsuru N, Oi M, Kakigi R, Okada M: Memory-based pre-attentive auditory N1 elicited by sound movement. Neurosci Res 73:248-251, 2012
13. Keceli S, Inui K, Okamoto H, Otsuru N, Kakigi R: Auditory sustained field responses to periodic noise. BMC Neurosci 13: 7, 2012
14. Yamashiro K, Inui K, Otsuru N, Urakawa T, Kakigi R: Temporal window of integration in the somatosensory modality: An MEG study. Clin Neurophysiol 122:2276-2281, 2011
15. Nishihara M, Inui K, Motomura E, Otsuru N, Ushida T, Kakigi R: Auditory N1 as a change-related automatic response. Neurosci Res 71:145-148, 2011
16. Otsuru N, Inui K, Yamashiro K, Urakawa T, Keceli S, Kakigi R: Effects of prior sustained tactile stimulation on the somatosensory response to the sudden change of intensity in humans: an magnetoencephalography study. Neuroscience 182:115 -124, 2011
17. Inui K, Urakawa T, Yamashiro K, Otsuru N, Takeshima Y, Nishihara M, Motomura E, Kida T, Kakigi R: Echoic memory of a single pure tone indexed by change-related brain activity. BMC Neurosci 11:135, 2010
18. Inui K, Urakawa T, Yamashiro K, Otsuru N, Nishihara M, Takeshima Y, Keceli S, Kakigi R: Non-linear laws of echoic memory and auditory change detection in humans. BMC Neurosci 11: 80, 2010
19. Yamashiro K, Inui K, Otsuru N, Kakigi R: Change-related response in the human auditory cortex: An MEG study. Psychophysiology 48:23-30, 2010
20. Otsuru N, Inui K, Yamashiro K, Miyazaki T, Takeshima Y, Kakigi R: Assessing A-delta fiber function with lidocaine using intra-epidermal electrical stimulation. J Pain 11:621-627, 2010
21. Mochizuki H, Inui K, Tanabe HC, Akiyama LF, Otsuru N, Yamashiro K, Sasaki A, Nakata H, Sadato N, Kakigi R: Time course of activity in itch-related brain regions: A combined MEG-fMRI study. J Neurophysiol 102:2657-2666, 2009
22. Otsuru N, Inui K, Yamashiro K, Miyazaki T, Ohsawa I, Takeshima Y, Kakigi R: Selective stimulation of C fibers by an Intra-epidermal needle electrode in humans. The Open Pain Journal 2:53-56, 2009
23. Yamashiro K, Inui K, Otsuru N, Kida T, Kakigi R: Automatic auditory off-response in humans: an MEG study. European Journal of Neuroscience 30:125-131, 2009
24. Yamashiro K, Inui K, Otsuru N, Kida T, Kakigi R: Somatosensory off response in humans: an MEG study. NeuroImage 44:1363-1368, 2009
25. Yamashiro K, Inui K, Otsuru N, Kida T, Akatsuka K, Kakigi R: Somatosensory off response in humans: an ERP study. Exp Brain Res 190:207-213, 2008
26. Mochizuki H, Inui K, Yamashiro K, Otsuru N, Kakigi R: Itching-related somatosensory evoked potentials. Pain 138:598-603, 2008
研究業績2011年 生理学研究所若手研究者育成支援 
2012年~2015年 科学研究費補助金 若手研究(B) 「知覚―運動ループの不一致が痛覚および変化検出機構に及ぼす影響」
2015年~2018年 科学研究費補助金 若手研究(B) 「自己身体認知の変化を誘発するリハビリテーション戦略の開発」
社会的活動愛知県理学療法学会学術誌部 部員 (2011年)
Frontiers in human neuroscience誌 review editor(2015年~現在に至る)
新潟疼痛懇話会 役員 (2017年~現在に至る)